Clinical or Health System Question in PICOT and Research Formats

Clinical question: PICOT Formats and One Hypothesis Format (must be safety, quality, novel care delivery, or policy/procedure)

At least one area needs to be PICOT & one a research hypothesis with the null stated as well like the examples below.

Online or clinical resources – List at least 2 resources for each. Please use APA format to list resources in this column.

Example Diagnosis Research Hypothesis:

Research hypothesis: A low D-dimer level (less than 500 ng/mL) has a high negative predictive value for acute pulmonary embolism (PE) among patients undergoing diagnostic pulmonary angiography (H₁). Null would be: A low D-dimer level has no predictive value for acute pulmonary embolism (PE) among patients undergoing diagnostic pulmonary angiography (H₀). (Goldhaber et al., 1993; Tran et al., 2019)

Goldhaber, S. Z., Simons, G. R., Elliott, C. G., Haire, W. D., Toltzis, R., Blacklow, S. C., . . . Weinberg, D. S. (1993). Quantitative plasma D-dimer levels among patients undergoing pulmonary angiography for suspected pulmonary embolism. JAMA, 270(23), 2819-2822.

Tran, H. A., Gibbs, H., Merriman, E., Curnow, J. L., Young, L., Bennett, A., . . . Nandurkar, H. (2019). New guidelines from the Thrombosis and Haemostasis Society of Australia and New Zealand for the diagnosis and management of venous thromboembolism. The Medical journal of Australia, 210(5), 227-235. doi:10.5694/mja2.50004

Example Diagnosis PICOT:

In patients with suspected deep vein thrombosis (P) is D-dimer assay (I) compared with ultrasound (C) more accurate in diagnosing deep vein thrombosis (O)?(Goldhaber et al., 1993; Tran et al., 2019)

Goldhaber, S. Z., Simons, G. R., Elliott, C. G., Haire, W. D., Toltzis, R., Blacklow, S. C., . . . Weinberg, D. S. (1993). Quantitative plasma D-dimer levels among patients undergoing pulmonary angiography for suspected pulmonary embolism. JAMA, 270(23), 2819-2822.

Tran, H. A., Gibbs, H., Merriman, E., Curnow, J. L., Young, L., Bennett, A., . . . Nandurkar, H. (2019). New guidelines from the Thrombosis and Haemostasis Society of Australia and New Zealand for the diagnosis and management of venous thromboembolism. The Medical journal of Australia, 210(5), 227-235. doi:10.5694/mja2.50004

Intervention Hypothesis:

State your research hypothesis (H₁ & H₀):

Intervention PICOT:

In _________________________________________(P) how does ___________________________________(I) compared with_______________________________(C) affect______________________________________(O) within _____________________________________(T)

Prognosis/prediction PICOT

In ________________________________________(P) how does __________________________________(I) compared with______________________________(C) influence/predict____________________________(O) over _____________________________________(T)

Diagnosis or diagnostic test: PICO

In ________________________________________(P) are/is ______________________________________(I) compared with______________________________(C) more accurate in diagnosing ___________________(O)

Etiology: PICOT

Are______________________________________(P) who have _________________________________(I) compared with those without __________________(C) at________ risk for/of _______________________(O) over ______________________________________(T)

Meaning: PIOT

How do _____________________________________(P) with_________________________________________(I) perceive_____________________________________(O) during ______________________________________(T)