Lewy Body Dementia
Lewy Body Dementia
Compare differential diagnostic features of neurocognitive disorders (Lewy Body Dement
· Explain the evidenced-based psychotherapy and psychopharmacologic treatment for your assigned neurocognitive disorder. (Lewy Body Dementia)
· Evaluate benefits and risks of neurocognitive therapies
· Identify the risks of different types of therapy and explain how the benefits of the therapy that might be achieved might outweigh the risks.
· Support your rationale with references to the Learning Resources or other academic resource (REFERENCES MUST BE LESS THAN 5 YEARS OLD)
PLEASE YOU MUST INCLUDE INTRODUCTION, CONCLUSION AND REFERENCES
Learning Resources
Required Readings
Sadock, B. J., Sadock, V. A., & Ruiz, P. (2014). Kaplan & Sadock’s synopsis of psychiatry: Behavioral sciences/clinical psychiatry (11th ed.). Philadelphia, PA: Wolters Kluwer.
· Chapter 21, “Neurocognitive Disorders” (pp. 694–741)
Gabbard, G. O. (2014). Gabbard’s treatment of psychiatric disorders (5th ed.). Washington, DC: American Psychiatric Publications.
· Chapter 63, “Delirium”
· Chapter 64, “Neurocognitive Disorder Due to Alzheimer’s Disease”
· Chapter 65, “Frontotemporal Neurocognitive Disorder”
· Chapter 66, “Vascular Neurocognitive Disorder”
· Chapter 67, “Neurocognitive Disorder Due to Parkinson’s Disease”
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.
· “Neurocognitive Disorders”
Stahl, S. M. (2014). Prescriber’s Guide: Stahl’s Essential Psychopharmacology (5th ed.). New York, NY: Cambridge University Press.
To access information on specific medications, click on The Prescriber’s Guide, 5th Ed. tab on the Stahl Online website and select the appropriate medication.
| Alzheimer disease | Delirium | Dementia | Parkinson’s disease dementia |
| caprylidene donepezil galantamine memantine rivastigmine | haloperidol (adjunct) lorazepam (adjunct) | donepezil galantamine memantine rivastigmine | rivastigmine pimavanserin |
Note: For more information on Pimavanserin, see:
Acadia Pharmaceuticals. (2017). Transform the treatment of Parkinson’s disease psychosis with NUPLAZID. Retrieved from https://www.nuplazidhcp.com/?gclid=CIHS5auvwtMCFQkaaQodrU0FGQ
U.S. Food and Drug Administration. (n. d.). Highlights of prescribing information: Nuplazid. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/207318lbl.pdf
Hopkins, S. A., & Chan, D. (2016). Key emerging issues in frontotemporal dementia. Journal of Neurology, 263(2), 407–413. doi:10.1007/s00415-015-7880-7
Walker, Z., Possin, K. L., Boeve, B. F., & Aarsland, D. (2017). Lewy body dementias. Focus, 15(1), 85–100. doi: 10.1176/appi.focus.15105
Required Media
Laureate Education (Producer). (2017a). A gentleman with a neurocognitive disorder [Multimedia file]. Baltimore, MD: Author.
Bolin, P. (2015, December 31). Neurocognitive disorders – CRASH! Medical review series [Video file]. Retrieved from https://www.youtube.com/watch?v=bQXOPITY9XM
Optional Resources
Kota, L. N., Bharath, S., Purushottam, M., Moily, N. S., Sivakumar, P. T., Varghese, M., . . . Jain, S. (2015). Reduced telomere length in neurodegenerative disorders may suggest shared biology. The Journal of Neuropsychiatry and Clinical Neurosciences, 27(2), e92–e96. doi:10.1176/appi.neuropsych.13100240
Lepkowsky, C. M. (2016). Neurocognitive disorder with Lewy bodies: Evidence-based diagnosis and treatment. Practice Innovations, 1(4), 234–242. doi:10.1037/pri0000031
Oltra-Cucarella, J., Pérez-Elvira, R., Espert, R., & Sohn McCormick, A. (2016). Are cognitive interventions effective in Alzheimer’s disease? A controlled meta-analysis of the effects of bias. Neuropsychology, 30(5), 631–652. doi:10.1037/neu0000283
