[SOLVED] Respond  on two different days who selected different factors th

Respond  on two different days who selected different factors than you, in one or more of the following ways: Offer alternative diagnoses and prescription of treatment options for osteoarthritis and rheumatoid arthritis. Share an insight from having read your colleague’s posting, synthesizing the information to provide new perspectives.                                                          Main Post                                                                     Arthritis             Arthritis is an inflammation of the joints. It can affect one joint or multiple joints. There are more than 100 different types of arthritis, with different causes and treatment methods. Two of the most common types are osteoarthritis (OA) and rheumatoid arthritis (RA) (Macon, B, Guy, L. 2017).  Osteoarthritis: Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage that cushions the ends of your bones wears down over time. Osteoarthritis can occur in any joint, it mainly affects the hands, knees, hips, and spine.  Rheumatoid Arthritis: Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by the persistent symmetric inflammation of multiple peripheral joints. It is characterized by the development of a chronic inflammatory proliferation of the synovial linings of diarthrodial joints, which leads to aggressive cartilage destruction and progressive bony erosions Pathophysiology of Osteoarthritis and Rheumatoid Arthritis             In both cases involving OA and RA, the etiology is fully not understood. The pathophysiology of OA articular cartilage is played by cell/extra-cellular matrix (ECM) interactions, which are mediated by cell surface integrins. “OA is a complex disease whose pathogenesis includes the contribution of biomechanical and metabolic factors which, altering the tissue homeostasis of articular cartilage and subchondral bone, determine the predominance of destructive over productive processes” (Lannone F, et al. 2003). In RA, damage is centered around the synovial linings of joints the synovium normally provides nutrients and lubrication to adjacent articular cartilage. RA synovium, in contrast, is markedly abnormal, with a greatly expanded lining layer (8–10 cells thick) composed of activated cells; a highly inflammatory interstitium replete with B cells, T cells, and macrophages; and vascular changes, including thrombosis and neovascularization” (Hammer, G. D., & McPhee, S. J, 2019). Factors: Age and Genetics             Many factors can play a role in OA and RA. The causes of RA and OA still remain unclear, there is several links to genetic and environmental factors that have been identified that predispose to the development of RA and OA.  Genetics is the first factor that plays a significant role in the development of RA and OA. In OA there is rare genetic defect that causes the body’s production of collagen to be disrupted, this can cause an early diagnosis. Another is an inherited trait where the bones don’t line up correctly causing wear and breakdown on the cartilage. Researchers have discovered the Gene FAAH that could be a cause of OA. With RA it can be a combination of genetics and environmental factors. “The most significant genetic risk factors for rheumatoid arthritis are variations in human leukocyte antigen (HLA) genes, especially the HLA-DRB1 gene. The proteins produced from HLA genes help the immune system distinguish the body’s own proteins from proteins made by foreign invaders (such as viruses and bacteria). Changes in other genes appear to have a smaller impact on a person’s overall risk of developing the condition” (NIH, 2019). RA affects women more than men possibly due to hormones changing in women with age.  Treatment and Diagnosis of RA and OA             Diagnosis RA in early stages can be difficult because early signs and symptoms mimic other disease. To diagnosis RA and OA, MRI or X-ray can help in diagnosis of the disease and progression. There is no blood test for OA but RA, laboratory test like ESR, or sed rate or C-reactive protein (CRP), Most of the time the levels will be elevated (Mayo Clinic, 2019), which may indicate the presence of an inflammatory process in the body. Other common blood tests look for rheumatoid factor and anti-cyclic citrullinated peptide (anti-CCP) antibodies. There is a physical exam that can determine redness, swelling, and pain in the joints, and will also check for reflexes and strength. There is no cure for OA or RA, but treatment with Disease-modifying antirheumatic drugs (DMARDs) can slow the progression and with RA can sometimes put patients in remission.  References Hammer, G. D., & McPhee, S. J. (2019). Pathophysiology of disease: An introduction to clinical  medicine (8th ed.). New York, NY: McGraw-Hill Education.   Iannone F, et al. (2003). The pathophysiology of osteoarthritis. Aging Clinical and Experimental  Research.15(5):364-72. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/14703002/?ncbi_mmode=std     Macon, B, Guy, L. (2017). Arthritis. Retrieved from https://www.healthline.com/health/arthritis   Mayo Clinic. (2019). Rheumatoid arthritis. Retrieved from https://www.mayoclinic.org/diseases- conditions/rheumatoid-arthritis/diagnosis-treatment/drc-20353653   Mayo Clinic. (2019). Osteoarthritis. Retrieved from https://www.mayoclinic.org/diseases- conditions/osteoarthritis/diagnosis-treatment/drc-20351930   National Institute of Health. (2019). Rheumatoid arthritis. Retrieved from  https://ghr.nlm.nih.gov/condition/rheumatoid-arthritis#resources

 

Struggling to find relevant content or pressed for time? – Don’t worry, we have a team of professionals to help you on
[SOLVED] Respond  on two different days who selected different factors th
Get a 15% Discount on this Paper
Order Now

Can’t find relevant content? Don’t worry– you have a team of professionals to help you.

All you need to do is fill in the order form in the upper right corner and upload the files that are crucial for your assignment. Also, don’t forget to specify whether your assignment has to be based upon a specific research, theory or method. After that, we will assign an expert to complete your order. You can always chat with your expert and ask any questions you have during the working process.

Calculate the price
Make an order in advance and get the best price
Pages (550 words)
$0.00
*Price with a welcome 15% discount applied.
Pro tip: If you want to save more money and pay the lowest price, you need to set a more extended deadline.
We know how difficult it is to be a student these days. That's why our prices are one of the most affordable on the market, and there are no hidden fees.

Instead, we offer bonuses, discounts, and free services to make your experience outstanding.
How it works
Receive a 100% original paper that will pass Turnitin from a top essay writing service
step 1
Upload your instructions
Fill out the order form and provide paper details. You can even attach screenshots or add additional instructions later. If something is not clear or missing, the writer will contact you for clarification.
Pro service tips
How to get the most out of your experience with MyCoursebay
One writer throughout the entire course
If you like the writer, you can hire them again. Just copy & paste their ID on the order form ("Preferred Writer's ID" field). This way, your vocabulary will be uniform, and the writer will be aware of your needs.
The same paper from different writers
You can order essay or any other work from two different writers to choose the best one or give another version to a friend. This can be done through the add-on "Same paper from another writer."
Copy of sources used by the writer
Our college essay writers work with ScienceDirect and other databases. They can send you articles or materials used in PDF or through screenshots. Just tick the "Copy of sources" field on the order form.
Testimonials
See why 20k+ students have chosen us as their sole writing assistance provider
Check out the latest reviews and opinions submitted by real customers worldwide and make an informed decision.
Nursing
Did not receive paper on time.
Customer 452693, November 9th, 2022
Social Work and Human Services
Excellent! Done earlier than needed and with more sources than needed! Great work!
Customer 452485, August 22nd, 2021
Strategic Management
Thank you very much for the help, really appreciate it
Customer 452821, June 27th, 2022
Nursing
Always perfect! Thank you!!!
Customer 452453, April 15th, 2021
Nurse
Great work! Thank you for the quality you put in each assignment.
Customer 452707, February 4th, 2022
Nursing
Great work. thank you again!
Customer 452707, August 7th, 2022
Nursing
Everything was done perfectly. Thank you.
Customer 452707, June 15th, 2022
Human Resources Management (HRM)
Thank you
Customer 452701, November 1st, 2022
Mental Wellness
The skilled writer did a good job. I will add a few more details. Thank you, great job...
Customer 452547, June 17th, 2021
Nursing
Writer went above and beyond. Can't believe how much work they put in for the price.
Customer 452707, July 10th, 2022
Social Work and Human Services
Great Work!
Customer 452587, August 31st, 2021
Criminal Justice
Looks good! Thank you Jason
Customer 452711, January 25th, 2022
11,595
Customer reviews in total
96%
Current satisfaction rate
3 pages
Average paper length
37%
Customers referred by a friend
OUR GIFT TO YOU
15% OFF your first order
Use a coupon FIRST15 and enjoy expert help with any task at the most affordable price.
Claim my 15% OFF Order in Chat

Get your perfect essay with a 15% discount. Use DC15

NEW

Thank you for choosing MyCoursebay. Your presence is a motivation to us. All papers are written from scratch. Plagiarism is not tolerated. Order now for a 15% discount

Order Now